BPC 157

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BPC 157 250 mcg/mL Oral Capsules
BPC-157 (Body protection compound) is a pentadecapeptide that potentially promotes wound healing
based on muscle and tendon restorative properties via angiogenic repair intensification. 1
It’s composed of
15 amino acids found in and accessed from human gastric juice. 3 BPC-157 has provided promising
results to support healing of multiple tissues in animal studies. 4 Such accelerated healing has been
demonstrated in skin, muscle, bone, ligament, and tendons.
The use of BPC-157 has primarily been utilized to promote accelerated healing in multiple tissues,
however, is an anti-ulcer peptide recognized for therapeutic effectiveness in inflammatory bowel disease
treatment. 5 Recent focus has centered on the peptides nervous system and intramuscular regenerative and
healing properties. BPC-157 has been recognized as a powerful angiomodulatory agent maximizing
vascular response, and, subsequent promotion of the healing process.6

Pevec et al. (2010) examined effects of pentadecapeptide BPC-157 on muscle healing impaired by
systemic corticosteroid application in rats.2
Following gastrocnemius muscle complex injury, rats
received BPC-157 intraperitoneally or local cream application and/or a corticosteroid. Findings suggest
BPC-157 comprehensively inverted systemic corticosteroid-impaired muscle healing, promoting swifter
muscle healing and functionality, likely an efficient therapeutic intervention to progress muscle healing
regardless of corticosteroid treatment. Chang et al. (2011) investigated action mechanisms of BPC- 157 in
accelerating healing of injured rat tendons. The researchers conclude, “BPC 157 promotes the ex vivo
outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration
of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway”
(Abstract).3 In related research using male Sprague-Dawley rats, Chang et al. (2014) found that BPC-157
augmented growth hormone (GH) receptor in tendon fibroblasts, perhaps actuating production effects of
GH, and, by extension, intensifying tendon healing.4

Suggested benefits:
 Accelerated skin, bone, ligament, and tendon repair;
 Favorable anti-allergen and anti-viral properties7
;
 Relief from inflammatory bowel conditions;
 Repair of the Brain-Gut Axis7
;
 Reverses opioid tolerance7
.