EverGreen Joint Support 300 caps
Glucosamine is the main nutrient that helps rebuild new cartilage, Chondroitin Sulfate seems to prevent further destruction of cartilage and MSM acts as an anti-inflammatory.
Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are major components of joint cartilage, glucosamine is vital for healthy joints.
Glucosamine is a compound found naturally in the body, made from glucose and the amino acid glutamine. Glucosamine is needed to produce glycosaminoglycan, a molecule used in the formation and repair of cartilage and other body tissues. Production of glucosamine slows with age.
Glucosamine is thought to stimulate synovial production of hyaluronic acid and is also claimed to inhibit cartilage degrading liposomal enzymes.
Glucosamine supplements are manufactured in a laboratory from chitin, a substance found in the shells of shrimp, crab, lobster, and other sea creatures.
The National Institutes of Health conducted a $12.5 million study on osteoarthritis pain. 79.2% of people in the moderate-to-severe pain subgroup who took glucosamine and chondroitin combination had reduced pain. compared to 70% who took 200 mg a day of Celebrex
According to the Nutrition Business Journal, glucosamine and chondroitin sales exceeded $1.7 billion in 2005. “because it works” Since glucosamine supplements may be made from shellfish, people with allergies to shellfish should avoid glucosamine unless it has been confirmed that it is from a non-shellfish source.
Chondroitin and is believed to prevent the destruction of cartilage by enzymes.
Chondroitin helps to keep cartilage healthy by absorbing fluid (particularly water) into the connective tissue it also gives cartilage elasticity. It may also block enzymes that break down cartilage, and it provides the building blocks for the body to produce new cartilage.
Methylsulfonylmethane AKA MSM:
MSM provides sulfur, a vital building block of joints, cartilage, skin, hair and nails, and methyl groups, which support many vital biochemical processes in the body, including energy production. MSM is a naturally-occurring nutrient found in small amounts of many foods. MSM helps maintain the structure of connective tissue by forming cross-linkages through disulfide bonds i.e. sulfur strengthens the tissues that make up the joint. Sulfur is critical to good joint health. Glycosaminoglycans (GAGs) are the fundamental building blocks of joint cartilage, and GAG molecules are linked together in chains by disulfide bonds. As the name implies, these bonds are between two sulfur atoms. The disulfide bridges reduce conformational flexibility of GAG chains, making cartilage firm and resilient. Cartilage integrity is thus a sulfur-dependent state.
When rigid fibrous tissue cells swell and become inflamed, pressure and pain result. Since MSM can restore flexibility and permeability to cell walls, fluids can pass through the tissues more easily. This helps equalize pressure and reduce or eliminate the cause of pain. Harmful substances such as lactic acid and toxins are allowed to flow out, while nutrients are permitted to flow in. This prevents the pressure buildup in cells that causes inflammation. MSM is an anti-oxidant that helps to clean the blood stream and flush toxins trapped in our cells.
MSM can also help with; Acne, Allergies, Arthritis, Asthma, Candida Yeast Infections, Carpal Tunnel Syndrome, Fragile Hair & Nails, Muscle Pain & Cramps, Skin Damage & Aging. MSM is virtually nontoxic. For a person that weighs 200 pounds they would have to consume 3.38lbs of MSM.
The best product to take is a combination of these 3 nutrients. A good general simplified explanation of the 3 nutrients is as follows: Glucosamine is the main nutrient that helps rebuild new cartilage, Chondroitin Sulfate seems to prevent further destruction of cartilage and MSM acts as an anti-inflammatory.